Uridine Monophosphate, also known as UMP, is one of four major components of ribonucleic acid (RNA); the other three are adenosine, guanine and cytidine. Below are products containing uridine in the form of RNA. However, uridine in this form is bioavailable. It is destroyed by the liver and gastrointestinal tract, and the food intake does not increase the level of uridine in the blood. In infant’s consuming breast milk or commercial infant formula, uridine monophosphate present as, and this is indeed a source of uridine bioavailability and enters the blood. Consumption of food rich RNA may lead to increased levels of purines (adenosine and guanosine) in the blood. High levels cause an increase in purines uric acid levels and can impair or lead to the development of diseases such as gout. Moderate consumption of yeast, about 5 grams per day will provide adequate levels of uridine, for health improvement with minimal side effects. It has been suggested that RNA from yeast products must be chemically reduced, if these products are consumed in large amounts (50 g or more per day) as a source of protein. However, such processing is expensive and is rarely used. Harvard researchers have reported that the addition of uridine and EPA / DHA omega-3 fatty acids in rats act as antidepressants. Uridine plays an important role in glycolysis pathway galactose. There is no catabolic process for the metabolism of galactose. Thus, the galactose into glucose and glucose metabolized in the general way. After converting incoming galactose-1-phosphate (Gal-1-P), it participates in the reaction with UDP-glucose, a glucose molecule attached to a molecule of UDP (uridine di-phosphate). This process is catalyzed by the enzyme galactose-1-phosphate uridiltransferazy and transmits the UDP galactose molecule. The result is a molecule UDP-galactose and glucose molecule-1-phosphate. This process continues for the galactose molecule glycolysis.

• Uridine can be found in many foods such as tomatoes, beer, and breast milk. Uridine can bypass the blood-brain barrier effectively by one of two neuro transporters known as equilibrate and concentrative. Uridine also when administered orally causes a production of CDP-choline.
• Uridine is a Ribonucleoside, which are the building blocks for both RNA and DNA. Uridine is one of the four essential components of RNA (ribonucleic acid), and is absorbed within the intestinal tract. Studies have shown that supplementation of Uridine along with Choline and fish oil increases synaptic formation and function, showing improvement in persons suffering from mild Alzheimer’s Disease. This nootropic may increase or raise dopamine levels within the brain.